Lean Six Sigma is a methodology that introduces concepts for identifying and removing the inefficiencies from tasks. The typical tasks that clinical researchers do every day can be improved so that less time is spent and increased quality can be injected. We will provide an overview of what Lean Six Sigma means and how to go about assessing any activity. Small groups will be tasked with a familiar process or task instruction to lean for themselves. Attendees will learn actionable take away tools to apply to their daily activities.